These reagents can perturb and manipulate sample-sample and sample-solvent interactions, as well as perturb water structure which can alter and improve both the solubility and crystallization of a sample. Additives can stabilize or engender conformity by specific interaction with the macromolecules. There are numerous reports of the use of additives to improve the quality and size of macromolecular crystals.^1-5

Additive screen reagent classifications include multivalent, salt, amino acid, dissociating agent, linker, polyamine, osmolyte, chaotrope, co-factor, reducing agent, chelating agent, polymer, carbohydrate, non-detergent, amphiphile, detergent, non-volatile organic and volatile organic.

Additive Screen contains 96 unique reagents, 1 ml each.

Additive Screen HT contains 96 unique reagents, 1 ml each, in a single Deep Well block.

Additive Screen 是一個試劑庫，可以影響生物大分子的溶解度和結(jié)晶，包括可溶性蛋白和膜蛋白。

這些試劑可以干擾和操縱樣品-樣品和樣品-溶劑的相互作用，以及可以改變和改善樣品溶解度和結(jié)晶的水結(jié)構(gòu)。添加劑可以通過與大分子的特定相互作用來穩(wěn)定或產(chǎn)生一致性。有許多關(guān)于使用添加劑來改善大分子晶體的質(zhì)量和尺寸的報道。 1-5

添加劑篩選試劑分類包括多價、鹽、氨基酸、解離劑、連接劑、多胺、滲透劑、離液劑、輔助因子、還原劑、螯合劑、聚合物、碳水化合物、非去污劑、兩親物、去污劑、非揮發(fā)性有機物和揮發(fā)性有機物。

Additive Screen 包含 96 種獨特的試劑，每種試劑 1 ml。

Additive Screen HT 在單個 Deep Well 模塊中包含 96 種獨特的試劑，每種試劑 1 ml。