beta Actin (ACTB) Mouse Monoclonal Antibody [Clone ID: OTI1]β肌動蛋白（ACTB）小鼠單克隆抗體[克隆ID：OTI1]

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 Product Data
Clone Name OTI1
Applications WB
Recommend Dilution WB 1:2000
Reactivity Human, Monkey, Mouse, Rat, Dog
Host Mouse
Clonality Monoclonal
Immunogen Synthetic peptide corresponding to the N terminal of human beta-actin conjugated to KLH.
Isotype IgG3
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 41.6 kDa
Gene Name actin, beta
 Reference Data
Protein Families ES Cell Differentiation/IPS
Protein Pathways Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Tight junction, Vibrio cholerae infection, Viral myocarditis

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

The use of this Antibodies has been cited in the following citations:
Aberrant PD-1 ligand expression contributes to the myocardial inflammatory injury caused by Coxsackievirus B infection ,Wang, T;Chen, S;Wang, X;Huang, Y;Qiu, J;Fei, Y;Chaulagain, A;Chen, Y;Wang, Y;Lin, L;Yan, B;Wang, Y;Wang, W;Zhao, W;Zhong, Z;, Antiviral Res. 2019 ,PubMed ID 30904424 [BETA-ACTIN]
Overexpression of grainyhead-like transcription factor 2 is associated with poor prognosis in human pancreatic carcinoma ,Wang, G;Pan, J;Zhang, L;Wang, C;, Oncol Lett 2019 ,PubMed ID 30675204 [BETA-ACTIN]
Moringa oleifera Leaf Petroleum Ether Extract Inhibits Lipogenesis by Activating the AMPK Signaling Pathway ,Xie, J;Wang, Y;Jiang, W;Luo, X;Dai, T;Peng, L;Song, S;Li, L;Tao, L;Shi, C;Hao, R;Xiao, R;Tian, Y;Sheng, J;, Front. Pharmacol. 2018 ,PubMed ID 30618744 [ACTB]
Overexpression of grainyhead?like transcription factor 2 is associated with poor prognosis in human pancreatic carcinoma ,Wang, G;Pan, J;Zhang, L;Wang, C;, Oncol Lett 2018 [BETA-ACTIN]
Pirfenidone suppresses bleomycin-induced pulmonary fibrosis and periostin expression in rats ,Song, X;Yu, W;Guo, F;, Exp Ther Med 2018 ,PubMed ID 30186404 [BETA-ACTIN]
Emodin Attenuates Autophagy Response to Protect the Pancreas From Acute Pancreatitis Failure ,Yu, X;Li, C;Song, H;Wang, X;Guo, Y;Cui, L;Liu, X;Chi, C;Liu, R;Yin, C;, Pancreas 2018 ,PubMed ID 29912852 [ACTB]
Role of microRNA-21 in uveal melanoma cell invasion and metastasis by regulating p53 and its downstream protein ,Wang, YC;Yang, X;Wei, WB;Xu, XL;, Int J Ophthalmol 2018 ,PubMed ID 30140627 [ACTB]
High C-X-C motif chemokine 5 expression is associated with malignant phenotypes of prostate cancer cells via autocrine and paracrine pathways ,Qi, Y;Zhao, W;Li, M;Shao, M;Wang, J;Sui, H;Yu, H;Shao, W;Gui, S;Li, J;Jia, X;Jiang, D;Li, Y;Zhang, P;Wang, S;Wang, W;, Int. J. Oncol. 2018 ,PubMed ID 29749439 [BETA-ACTIN]
An ellagic acid isolated from Clerodendrum viscosum leaves ameliorates iron-overload induced hepatotoxicity in Swiss albino mice through inhibition of oxidative stress and the apoptotic pathway ,Shendge, AK;Basu, T;Panja, S;Chaudhuri, D;Mandal, N;, Biomed. Pharmacother. 2018 ,PubMed ID 29990833 [ACTB]
MicroRNA-644a promotes apoptosis of hepatocellular carcinoma cells by downregulating the expression of heat shock factor 1 ,Liang, W;Liao, Y;Li, Z;Wang, Y;Zheng, S;Xu, X;Ran, F;Tang, B;Wang, Z;, Cell Commun. Signal 2018 ,PubMed ID 29898735 [ACTB]
SKLB-23bb, A HDAC6-Selective Inhibitor, Exhibits Superior and Broad-Spectrum Antitumor Activity via Additionally Targeting Microtubules ,Wang, F;Zheng, L;Yi, Y;Yang, Z;Qiu, Q;Wang, X;Yan, W;Bai, P;Yang, J;Li, D;Pei, H;Niu, T;Ye, H;Nie, C;Hu, Y;Yang, S;Wei, Y;Chen, L;, Mol. Cancer Ther. 2018 ,PubMed ID 29610282 [ACTB]
A natural antioxidant, tannic acid mitigates iron-overload induced hepatotoxicity in Swiss albino mice through ROS regulation ,Basu, T;Panja, S;Shendge, AK;Das, A;Mandal, N;, Environ. Toxicol. 2018 ,PubMed ID 29446234 [ACTB]
Pre-B cell leukemia transcription factor 3 induces inflammatory responses in human umbilical vein endothelial cells and murine sepsis via acting a competing endogenous RNA for high mobility group box 1 protein ,Zhang, Y;Feng, J;Cui, J;Yang, G;Zhu, X;, Mol Med Rep 2018 ,PubMed ID 29484406 [ACTB]
Inhibition of FASN expression enhances radiosensitivity in human non-small cell lung cancer ,Zhan, N;Li, B;Xu, X;Xu, J;Hu, S;, Oncol Lett 2018 [BETA-ACTIN]
Growth differentiation factor?5 induces tenomodulin expression via phosphorylation of p38 and promotes viability of murine mesenchymal stem cells from compact bone ,Qu, Y;Zhou, L;Lv, B;Wang, C;Li, P;, Mol Med Rep 2017 ,PubMed ID 29286087 [beta Actin]
T-cell immunoglobulin mucin-3 as a potential inducer of the epithelial-mesenchymal transition in hepatocellular carcinoma ,Lin, H;Yang, B;Teng, M;, Oncol Lett 2017 ,PubMed ID 29113224 [ACTB]
FMNL2 destabilises COMMD10 to activate NF-κB pathway in invasion and metastasis of colorectal cancer ,Yang, SS;Li, XM;Yang, M;Ren, XL;Hu, JL;Zhu, XH;Wang, FF;Zeng, ZC;Li, JY;Cheng, ZQ;Liao, WT;Ding, YQ;Guan, J;Liang, L;, Br. J. Cancer 2017 ,PubMed ID 28817833 [BETA]
CCDC134 serves a crucial role in embryonic development ,Yu, B;Zhang, T;Xia, P;Gong, X;Qiu, X;Huang, J;, Int. J. Mol. Med.2017 ,PubMed ID 29115376 [ACTB]
Inhibition of autophagy potentiates the proliferation inhibition activity of microRNA?7 in human hepatocellular carcinoma cells ,Wang, Y;Wang, Q;Song, J;, Oncology Letters 2017 [BETA-ACTIN]
Heat shock factor 1 inhibits the mitochondrial apoptosis pathway by regulating second mitochondria-derived activator of caspase to promote pancreatic tumorigenesis ,Liang, W;Liao, Y;Zhang, J;Huang, Q;Luo, W;Yu, J;Gong, J;Zhou, Y;Li, X;Tang, B;He, S;Yang, J;, J. Exp. Clin. Cancer Res. 2017 ,PubMed ID 28482903 [ACTB]
Protocadherin 7 inhibits cell migration and invasion through E-cadherin in gastric cancer ,Chen, HF;Ma, RR;He, JY;Zhang, H;Liu, XL;Guo, XY;Gao, P;, Tumour Biol. 2017 ,PubMed ID 28381163 [ACTB]
MicroRNA-181c Ameliorates Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats ,Fang, C;Li, Q;Min, G;Liu, M;Cui, J;Sun, J;Li, L;, Mol. Neurobiol 2016 ,PubMed ID 27933582 [ACTB]
Aging asymmetry: systematic survey of changes in age-related biomarkers in the annual fish Nothobranchius guentheri ,Dong, Y;Cui, P;Li, Z;Zhang, S;, Fish Physiol. Biochem. 2016 ,PubMed ID 27614442 [ACTB]