Sigma 阿霉素 鹽酸鹽
產(chǎn)品編號 D1515 | CAS號 25316-40-9 | SIGMA
Frequently Asked Questions
Frequently Asked Questions
are available for this Product.
包裝:10 mg in glass bottle?Biochem/physiol Actions
Naturally fluorescent anthracycline antibiotic, anticancer drug. Doxorubicin is a substrate of MRP1 which was first cloned from a DOX-resistant lung cancer cell line. Fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (Golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes.
法律信息
Adriamycin 為以下機(jī)構(gòu)的注冊商標(biāo)： RDF Pharmacia & Upjohn S.P.A.
Protocols & Applications
| Related Categories | Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics, |
| assay | 98.0-102.0% (HPLC) |
| mp | 216?°C (dec.)(lit.) |
| solubility | H2O: soluble50?mg/mL, clear |
| Mode of action | DNA synthesis | interferes |
| antibiotic activity spectrum | viruses |
| storage temp. | 2-8°C |