R4500 (-)-核黃素 from Eremothecium ashbyii, ≥98%化學(xué)性質(zhì)：黃色至橙黃色或紅黃色結(jié)晶性固體，微有特殊氣味，味淡苦，對(duì)光敏感。有三種不同水中溶解度的結(jié)晶型。干燥時(shí)不被散射光影響，但在堿性溶液中易被光影響變質(zhì)。在暗中對(duì)無(wú)機(jī)酸穩(wěn)定。易溶于堿性稀溶液，微溶于環(huán)己烷、乙酸異戊酯和苯酚，極微溶于乙醇、等滲氯化鈉溶液，不溶于乙醚、氯仿、丙酮和苯。極微溶水，水溶液呈黃綠色，飽和水溶液呈中性。pH 5.5-7.2(0.1g/L,H2O,20℃)。熔點(diǎn) 275-290℃(dec.)。比旋光 [α]20/D-135o(c=5,0.05M,NaOH)。用途：丙烯酰胺凝膠聚合作用的光催化劑；配制組織培養(yǎng)基；生命科學(xué)；細(xì)菌血清檢驗(yàn)中制備鉤端螺旋體培養(yǎng)基。儲(chǔ)存：常溫危害聲明：對(duì)環(huán)境無(wú)危害。預(yù)防聲明：滅火：耐醇泡沫，干粉或二氧化碳滅火。避免禁忌物。

R9504,(?)-核黃素,≥98%

BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98%

別名:乳黃素, 維生素 B2, 維生素 G

Empirical Formula (Hill Notation):C17H20N4O6

CAS號(hào):83-88-5

分子量:376.36

Beilstein/REAXYS Number:97825

EC 號(hào):201-507-1

MDL編號(hào):MFCD00005022

eCl@ss:34058005

PubChem化學(xué)物質(zhì)編號(hào):24899415

NACRES:NA.75

R9504-25G ￥392.11

R9504-100G ￥1,309.67

形式

powder

應(yīng)用

cell culture | insect: suitable

cell culture | mammalian: suitable

顏色yellow to orange

mp 290 °C (dec.) (lit.)

溶解性0.1 M NaOH: 10 mg/mL, clear, yellow to orange

儲(chǔ)存溫度room temp

說(shuō)明

一般描述

核黃素是一種可溶于水的必需維生素。牛奶和雞蛋是它的主要來(lái)源。核黃素在所有組織中通常與酶結(jié)合。核黃素在血漿中定位時(shí)，與白蛋白和特異性免疫球蛋白結(jié)合。

應(yīng)用

(-)-核黃素已用于實(shí)驗(yàn)小鼠腹腔注射給藥，以研究其對(duì)大腦中動(dòng)脈阻塞卒中的保護(hù)作用。它也可與克雷布斯液一起使用，以體外模擬類缺血狀態(tài)。

包裝

25, 100 g in glass bottle

生化/生理作用

核黃素是活性輔酶因子核黃素 5′ -單磷酸鹽（也稱為黃素單核苷酸或 FMN）和黃素腺嘌呤二核苷酸 (FAD)的前體。飲食中的核黃素缺乏會(huì)導(dǎo)致一種稱為阿里波黃素沉積癥的綜合征，其癥狀包括唇炎、口角炎、舌炎、角膜炎和脂溢性皮炎。核黃素具有抗腫瘤發(fā)展和心血管疾病的保護(hù)作用。其缺乏常影響涉及氧化還原反應(yīng)的代謝。核黃素對(duì)鐵的吸收、胃腸道發(fā)育、神經(jīng)發(fā)生、角膜血管化和角膜混濁都有重要作用。

S2424 豆甾醇 ~95%

S7501,琥珀酸greener alternativeReagentPlus?, BioRenewable, ≥99.0%別名:丁二酸分子式:HOOCCH2CH2COOHCAS號(hào):110-15-6分子量:118.09Beilstein/REAXYS Number:1754069EC 號(hào):203-740-4MDL編號(hào):MFCD00002789PubChem化學(xué)物質(zhì)編號(hào):24899751NACRES:NA.71S7501-500G￥942.14S7501-1KG￥1,364.42S7501-5KG￥3,526.36

S9637 丁二酸鈉 二元 六水合物 BioReagent, suitable for cell culture, suitable for insect cell culture

Sigma-Aldrich，琥珀酸鈉 二元 六水合物，BioReagent, suitable for cell culture, suitable for insect cell culture

別名:丁二酸 二鈉鹽, 琥珀酸 二鈉鹽

線性分子式:NaOOCCH2CH2COONa · 6H2O

CAS號(hào):6106-21-4

分子量:270.14

Beilstein:3921044

EC 號(hào):205-778-7

MDL編號(hào):MFCD00149117

PubChem化學(xué)物質(zhì)編號(hào):24899848

NACRES:NA.71

訂貨編號(hào)包裝規(guī)格?價(jià)格?

S9637-100G100 G ￥470.35

S9637-500G500 G ￥1,703.70

屬性

質(zhì)量水平

300

產(chǎn)品線

BioReagent

應(yīng)用

cell culture | insect: suitable

cell culture | mammalian: suitable

溶解性

H2O: 100 mg/mL, clear, colorless

說(shuō)明

包裝

100, 500 g in poly bottle

應(yīng)用

在細(xì)胞培養(yǎng)應(yīng)用中用作 TCA（三羧酸循環(huán)） 補(bǔ)充劑。

安全信息

Storage Class Code

13 – Non Combustible Solids

WGK

WGK 1

閃點(diǎn)(F)

Not applicable

閃點(diǎn)(C)

Not applicable

個(gè)人防護(hù)裝備

dust mask type N95 (US), Eyeshields, Gloves

論文

LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.

Georgia L Isom et al.

Cell, 181(3), 653-664 (2020-05-04)

Gram-negative bacteria are surrounded by an outer membrane composed of phospholipids and lipopolysaccharide, which acts as a barrier and contributes to antibiotic resistance. The systems that mediate phospholipid trafficking across the periplasm, such as MCE (Mammalian Cell Entry) transporters, have…

Specific Effects of Trabectedin and Lurbinectedin on Human Macrophage Function and Fate-Novel Insights.

Adrián Povo-Retana et al.

Cancers, 12(10) (2020-10-24)

Tumor-associated macrophages (TAMs) play a crucial role in suppressing the immunosurveillance function of the immune system that prevents tumor growth. Indeed, macrophages can also be targeted by different chemotherapeutic agents improving the action over immune checkpoints to fight cancer. Here…

Conditionally replicative adenoviral vectors for imaging the effect of chemotherapy on pancreatic cancer cells.

Jun Kimura et al.

Cancer science, 104(8), 1083-1090 (2013-05-18)

Pancreatic cancer has a poor prognosis after complete macroscopic resection combined with chemotherapy. Even after neoadjuvant chemotherapy, R0 resection is often not possible. Moreover, current imaging techniques cannot reliably distinguish viable cancer cells from scar tissue at the resectional margin….

Oxidative damage of rat liver mitochondria during exposure to t-butyl hydroperoxide. Role of Ca2? ions in oxidative processes.

Ilya B Zavodnik et al.

Life sciences, 92(23), 1110-1117 (2013-05-07)

The present study was designed for further evaluation of the biochemical mechanism of hepatic mitochondrial dysfunction under oxidative damages induced by organic hydroperoxide, tert-butyl hydroperoxide (tBHP), for estimation of the molecular targets impaired during oxidative stress, and for investigation of…

Acquired resistance to gemcitabine and cross-resistance in human pancreatic cancer clones.

Hiroshi Yoneyama et al.

Anti-cancer drugs, 26(1), 90-100 (2014-09-05)

The efficacy of gemcitabine (GEM), a standard treatment agent for pancreatic cancer, is insufficient because of primary or acquired resistance to this drug. Patients with tumors intrinsically sensitive to GEM gradually acquire resistance and require a shift to second agents…

T109 L-(+)-酒石酸 ≥99.5%

T1270

Sigma-Aldrich

硫胺 鹽酸鹽

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

別名:維生素B1 鹽酸鹽, 硫胺素 鹽酸鹽

Empirical Formula (Hill Notation):C12H17ClN4OS · HCl

CAS號(hào):67-03-8

分子量:337.27

Beilstein:3851771

EC 號(hào):200-641-8

MDL編號(hào):MFCD00012780

eCl@ss:34058006

PubChem化學(xué)物質(zhì)編號(hào):24899952

NACRES:NA.75

訂貨編號(hào)包裝規(guī)格? ? ? ? 價(jià)格

T1270-25G25 G? ? ? ?￥690.43

T1270-100G100 G? ? ? ￥1,402.33

生物來(lái)源

synthetic (organic)

產(chǎn)品線

BioReagent

測(cè)定

≥99.0% (HPLC)

形式

powder

分子量

Mw 337.27 g/mol

應(yīng)用

cell culture | insect: suitable

cell culture | mammalian: suitable

cell culture | plant: suitable

顏色

white

mp

250 °C (dec.) (lit.)

溶解性

H2O: 50 mg/mL, clear, colorless

相關(guān)類別

Plant Culture Media

Vitamins

說(shuō)明

包裝

25, 100 g in poly bottle

應(yīng)用

在培養(yǎng)的細(xì)胞中支持能量代謝和氨基酸合成。存在于許多傳統(tǒng)無(wú)血清配方中。

安全信息

象形圖

Exclamation mark

GHS07

警示用語(yǔ)：

Warning

危險(xiǎn)聲明

H319

預(yù)防措施聲明

P264 – P280 – P305 + P351 + P338 – P337 + P313

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 – Combustible Solids

WGK

WGK 1

閃點(diǎn)(F)

Not applicable

閃點(diǎn)(C)

Not applicable

個(gè)人防護(hù)裝備

Eyeshields, Gloves, type N95 (US)

參考論文

PasT of Escherichia coli sustains antibiotic tolerance and aerobic respiration as a bacterial homolog of mitochondrial Coq10.

Cinzia Fino et al.

MicrobiologyOpen, 9(8), e1064-e1064 (2020-06-20)

Antibiotic-tolerant persisters are often implicated in treatment failure of chronic and relapsing bacterial infections, but the underlying molecular mechanisms have remained elusive. Controversies revolve around the relative contribution of specific genetic switches called toxin-antitoxin (TA) modules and global modulation of…

Improved growth and morphological plasticity of Haloferax volcanii.

Roshali T de Silva et al.

Microbiology (Reading, England), 167(2) (2021-01-19)

Some microbes display pleomorphism, showing variable cell shapes in a single culture, whereas others differentiate to adapt to changed environmental conditions. The pleomorphic archaeon Haloferax volcanii commonly forms discoid-shaped (‘plate’) cells in culture, but may also be present as rods…

Isolation and propagation of leptospires at 37?°C directly from the mammalian host.

Richard L Hornsby et al.

Scientific reports, 10(1), 9620-9620 (2020-06-17)

The causative agent of leptospirosis includes multiple serovars and species of pathogenic leptospires that are excreted via urine from reservoir hosts of infection. Primary isolation takes weeks to months, and is limited to semi-solid media at 28-30?°C. Here we present…

Conjugation Protocol Optimised for Roseburia inulinivorans and Eubacterium rectale.

Paul O Sheridan et al.

Bio-protocol, 10(7), e3575-e3575 (2021-03-05)

Roseburia and Eubacterium species of the human gut microbiota play an important role in the maintaince of human health, partly by producing butyrate, the main energy source of our colonic epithelial cells. However, our knowledge of the biochemistry and physiology…

Gene expression differences in infected and noninfected middle ear complementary DNA libraries.

Joseph E Kerschner et al.

Archives of otolaryngology–head & neck surgery, 135(1), 33-39 (2009-01-21)

To investigate genetic differences in middle ear mucosa (MEM) with nontypeable Haemophilus influenzae (NTHi) infection. Genetic upregulation and downregulation occurs in MEM during otitis media (OM) pathogenesis. A comprehensive assessment of these genetic differences using the techniques of complementary DNA…

默克ICP元素分析標(biāo)準(zhǔn)溶液

Element ICP Standard Solution 1000 mg/L

Accreditation:Merck KGaA, Darmstadt, Germany is accredited by the German accreditation authority as registered reference material producer

(D-RM-15185-01-00) in accordance with ISO 17034.

Merck KGaA, Darmstadt, Germany – Calibration laboratory is accredited by the German accreditation authority as registered Calibration Laboratory (D-K-15185-01-00) according to

DIN EN ISO/IEC 17025.

Description of CRM:Element ICP standard solution 1000 mg/l

Expiry date:4 years

Storage:+15°C to +25°C tightly closed in the original container

Specification:956 – 1011 mg/kg

170301 Al Aluminium ICP Standard ± 5 mg/kg 170302 Sb Antimony ICP Standard ± 5 mg/kg 170303 As Arsenic ICP Standard ± 5 mg/kg 170304 Ba Barium ICP Standard ± 5 mg/kg 170305 Be Beryllium ICP Standard ± 5 mg/kg 170306 Bi Bismuth ICP Standard ± 5 mg/kg 170307 B Boron ICP Standard ± 5 mg/kg 170309 Cd Cadmium ICP Standard ± 5 mg/kg 170308 Ca Calcium ICP Standard ± 5 mg/kg 170311 Ce Cerium ICP Standard ± 5 mg/kg 170310 Cs Cesium ICP Standard ± 5 mg/kg 170312 Cr Chromium ICP Standard ± 5 mg/kg 170313 Co Cobalt ICP Standard ± 5 mg/kg 170314 Cu Copper ICP Standard ± 5 mg/kg 170315 Dy Dysprosium ICP Standard ± 5 mg/kg 170316 Er Erbium ICP Standard ± 5 mg/kg 170317 Eu Europium ICP Standard ± 5 mg/kg 170318 Gd Gadolinium ICP Standard ± 5 mg/kg 170319 Ga Gallium ICP Standard ± 6 mg/kg 170320 Ge Germanium ICP Standard ± 5 mg/kg 170321 Au Gold ICP Standard ± 5 mg/kg 170322 Hf Hafnium ICP Standard ± 5 mg/kg 170323 Ho Holmium ICP Standard ± 5 mg/kg 170324 In Indium ICP Standard ± 5 mg/kg 170325 Ir Iridium ICP Standard ± 8 mg/kg (*)

170326 Fe Iron ICP Standard ± 5 mg/kg 170327 La Lanthanum ICP Standard ± 5 mg/kg 170328 Pb Lead ICP Standard ± 5 mg/kg 170329 Li Lithium ICP Standard ± 6 mg/kg 170330 Lu Lutetium ICP Standard ± 5 mg/kg 170331 Mg Magnesium ICP Standard ± 5 mg/kg 170332 Mn Manganese ICP Standard ± 5 mg/kg 170333 Hg Mercury ICP Standard ± 7 mg/kg 170334 Mo Molybdenum ICP Standard ± 5 mg/kg 170335 Nd Neodymium ICP Standard ± 6 mg/kg 170336 Ni Nickel ICP Standard ± 5 mg/kg 170337 Nb Niobium ICP Standard ± 5 mg/kg 170338 Os Osmium ICP Standard ± 5 mg/kg (*) 170339 Pd Palladium ICP Standard ± 5 mg/kg 170340 P Phosphorus ICP Standard ± 5 mg/kg 170341 Pt Platinum ICP Standard ± 5 mg/kg 170342 K Potassium ICP Standard ± 5 mg/kg 170343 Pr Praseodymium ICP Standard ± 9 mg/kg 170344 Re Rhenium ICP Standard ± 6 mg/kg 170345 Rh Rhodium ICP Standard ± 6 mg/kg 170346 Rb Rubidium ICP Standard ± 8 mg/kg 170347 Ru Ruthenium ICP Standard ± 8 mg/kg (*) 170348 Sm Samarium ICP Standard ± 6 mg/kg 170349 Sc Scandium ICP Standard ± 5 mg/kg 170350 Se Selenium ICP Standard ± 7 mg/kg 170365 Si Silicon ICP Standard ± 5 mg/kg 170352 Ag Silver ICP Standard ± 5 mg/kg 170353 Na Sodium ICP Standard ± 5 mg/kg 170355 S Sulfur ICP Standard ± 5 mg/kg 170354 Sr Strontium ICP Standard ± 5 mg/kg 170356 Ta Tantalum ICP Standard ± 5 mg/kg 170357 Te Tellurium ICP Standard ± 5 mg/kg 170358 Tb Terbium ICP Standard ± 5 mg/kg 170359 Tl Thallium ICP Standard ± 5 mg/kg 170361 Tm Thulium ICP Standard ± 6 mg/kg 170362 Sn Tin ICP Standard ± 5 mg/kg 170363 Ti Titanium ICP Standard ± 5 mg/kg 170364 W Tungsten ICP Standard ± 5 mg/kg 170366 V Vanadium ICP Standard ± 5 mg/kg 170367 Yb Ytterbium ICP Standard ± 5 mg/kg 170368 Y Yttrium ICP Standard ± 5 mg/kg 170369 Zn Zinc ICP Standard ± 5 mg/kg 170370 Zr Zirconium ICP Standard ± 5 mg/kg

T3251 (±)-α-生育酚 synthetic, ≥96% (HPLC)

別名:

維生素 E, DL-α-生育酚

分子式：C29H50O2

CAS號(hào):10191-41-0

分子量:430.71

Beilstein/REAXYS Number:94012

EC 號(hào):233-466-0

MDL編號(hào):MFCD00006848

eCl@ss:34058016

PubChem化學(xué)物質(zhì)編號(hào):24900118

NACRES:NA.77

包裝? ? ? ? ? ? ? ? ? ?規(guī)格? ? ? 價(jià)格 ?

T3251-5G ????????5 G ? ?￥186.73

T3251-25G 25 G? ? ￥400.52

T3251-100G 100 G? ?￥1,125.69

T3251-500G 500 G? ? ￥3,080.69

生物來(lái)源

synthetic

測(cè)定

≥96% (HPLC)

形式

liquid

應(yīng)用

HPLC: suitable

顏色

faint brown to brown

yellow to very dark yellow

溶解性

H2O: insoluble

acetone: miscible

chloroform: miscible

ethanol: miscible

vegetable oils: miscible

密度

0.950 g/mL at 20 °C (lit.)

儲(chǔ)存溫度

2-8°C

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

InChI key

GVJHHUAWPYXKBD-UHFFFAOYSA-N

L-酪氨酸reagent grade, ≥98% (HPLC)

別名:3-(4-對(duì)羥苯基)-L-丙氨酸, (S)-2-氨基-3-對(duì)羥苯基丙酸

分子式:4-(HO)C6H4CH2CH(NH2)CO2H

CAS號(hào):60-18-4

分子量:181.19

Beilstein/REAXYS Number:392441

EC 號(hào):200-460-4

MDL編號(hào):MFCD00002606

eCl@ss:32160406

PubChem化學(xué)物質(zhì)編號(hào):24900164

NACRES:NA.26

等級(jí)：試劑級(jí)reagent grade

含量：≥98% (HPLC)

形態(tài)：粉末powder

應(yīng)用：detection: suitable

顏色：white to off-white

熔點(diǎn)mp：>300 °C (dec.) (lit.)

溶解性：1 M HCl: soluble 50 mg/mL

應(yīng)用

L-酪氨酸已被用于制備用于酪氨酸酶測(cè)定的酪氨酸溶液。它也被用于測(cè)定胃蛋白酶的活性。

包裝：50, 100, 500 g in poly bottle；1 kg in poly bottle

生化/生理作用

L-酪氨酸是一種具有極性側(cè)鏈的非必需氨基酸。細(xì)胞可利用它來(lái)合成在信號(hào)轉(zhuǎn)導(dǎo)中發(fā)揮作用的蛋白質(zhì)。L-酪氨酸是一種蛋白原氨基酸，其可作為激酶轉(zhuǎn)移的磷酸基團(tuán)的接收者。

其他說(shuō)明

多巴胺和其他兒茶酚胺的氨基酸前體

T3754 reagent grade, ≥98% (HPLC) 試劑級(jí)

訂貨編號(hào)
包裝規(guī)格 價(jià)格
T3754-50G 50 G 613
T3754-100G 100 G 1009
T3754-500G 500 G 3667
T3754-1KG 1 KG 5047

T8566 from non-animal source, ? meets EP, USP testing specifications, suitable for cell culture, 99.0-101.0% 非動(dòng)物源，藥典級(jí)細(xì)胞培養(yǎng)用

訂貨編號(hào)
包裝規(guī)格 價(jià)格
T8566-10MG 10 MG 242
T8566-25G 25 G 369
T8566-100G 100 G 1292
T8566-1KG 1 KG 6318

93829 BioUltra, ≥99.0% (NT) 生物超純級(jí)

訂貨編號(hào)
包裝規(guī)格 價(jià)格
93829-25G 25 G 499
93829-100G 100 G 1881

PHR1097 Pharmaceutical Secondary ? Standard; Certified Reference Material 認(rèn)證標(biāo)準(zhǔn)品

訂貨編號(hào)
包裝規(guī)格 價(jià)格
PHR1097-1G 1 G 991

T4321 PharmaGrade, Ajinomoto, EP, ? USP, manufactured under appropriate GMP controls for pharma or ? biopharmaceutical production, suitable for cell culture 藥典級(jí)，細(xì)胞培養(yǎng)用

訂貨編號(hào)
包裝規(guī)格 價(jià)格
T4321-100G 100 G 2224
T4321-1KG 1 KG 8980
T4321-10KG 10 KG 53822
T4321-25KG 25 KG 116572

1.08371 for biochemistry 生化級(jí)

訂貨編號(hào)
包裝規(guī)格 價(jià)格
1083710025 25 G 486
1083710100 100 G 661
1083711000 1 KG 3531

1705006 United States Pharmacopeia ? (USP) Reference Standard 美國(guó)藥典標(biāo)準(zhǔn)品

訂貨編號(hào)
包裝規(guī)格 價(jià)格
1705006-500MG 500 MG 4164

91515 certified reference ? material,?TraceCERT? 認(rèn)證標(biāo)準(zhǔn)品

訂貨編號(hào)
包裝規(guī)格 價(jià)格
91515-100MG 100 MG 1355

W373605 FG 食品級(jí)

訂貨編號(hào)
包裝規(guī)格 價(jià)格
W373605-SAMPLE
599
W373605-100G 100 G 930
W373605-1KG 1 KG 2269

1.08378 EMPROVE??EXPERT ? Ph Eur,JP,USP

訂貨編號(hào)
包裝規(guī)格 價(jià)格
1083781000
13511

V900426 Vetec?, ? reagent grade, ≥98% 試劑級(jí)

訂貨編號(hào)
包裝規(guī)格 價(jià)格
V900426-100G 100 G 179
V900426-500G 500 G 815

8.16021 for synthesis 合成級(jí)
訂貨編號(hào) 包裝規(guī)格 價(jià)格
8160210025 25 G 184
8160210100 100 G 261

T2900000 European Pharmacopoeia (EP) ? Reference Standard 歐洲藥典標(biāo)準(zhǔn)品

訂貨編號(hào)
包裝規(guī)格 價(jià)格
T2900000
2557