Molecular Dimensions 蛋白結(jié)晶培養(yǎng)箱

Molecular Dimensions 蛋白結(jié)晶培養(yǎng)箱

上海金畔生物代理Molecular Dimensions品牌蛋白結(jié)晶試劑耗材工具等,我們將竭誠為您服務(wù),歡迎訪問Molecular Dimensions官網(wǎng)或者咨詢我們獲取更多相關(guān)Molecular Dimensions品牌產(chǎn)品信息。

Temperature controlled cabinets specifically designed for crystal growth.

All have temperature programming and can be further customised with accessories such as lighting, glazed door, extra shelves, instrument cable ports and humidity control. These incubators need only a small floor space. They have a white interior with easily-cleaned plastic-coated wire shelves, adjustable at 35mm intervals to provide maximum flexibility of positioning. Temperature control is via an electronic controller with digital display, over/under temperature safety cut-outs and warning alarms. The doors are lockable and have a magnetic seal. The large workspace door can be opened wide to provide full-width access.

Molecular Dimensions Cooled Crystallisation Incubators are an economical alternative to building temperature-controlled rooms, and provide much more precise control of crystal growth temperature.

Features:

  • 100, 160, 230, and 400-litre models
  • Temperature range 0°C to 50°C
  • Temperature accuracy ± 0.5°C for precise crystal growth conditions
  • Virtually vibration free for undisturbed experiments
  • Easy-to-use control panel
  • Small foot-print maximises precious floor space in the laboratory

專為晶體生長而設(shè)計的溫控柜。
所有產(chǎn)品都具有溫度程序,并可進一步定制照明、玻璃門、額外擱板、儀器電纜端口和濕度控制等配件。這些孵化器只需要很小的占地面積。它們的內(nèi)部為白色,帶有易于清潔的塑料涂層金屬絲架,可按 35 毫米的間隔進行調(diào)節(jié),以提供最大的定位靈活性。溫度控制是通過帶有數(shù)字顯示、超溫/超溫安全切斷和警告警報的電子控制器進行的。門可上鎖并帶有磁性密封。大工作區(qū)門可以打開很寬,以提供全寬的訪問。

分子尺寸冷卻結(jié)晶培養(yǎng)箱是建造溫控室的經(jīng)濟替代方案,可以更精確地控制晶體生長溫度。

特征:

100、160、230 和 400 升型號
溫度范圍 0°C 至 50°C
溫度精度 ± 0.5°C,適用于精確的晶體生長條件
對于不受干擾的實驗幾乎沒有振動
易于使用的控制面板
占地面積小,可最大限度地利用實驗室寶貴的占地面積

400 litre internal volume cooled crystallization incubator.

Precise and constant temperature
Temperature is controlled electronically. A continuously-running fan guarantees high accuracy of temperature control throughout the cabinet interior and over time, according to DIN-58945.
Heating and cooling
The continuously adjustable fan-mounted electrical resistance heater has low thermal “drag”. It is controlled by a solid-state relay, avoiding steps and relay contact breaking. This design provides maximal accuracy of temperature with “coasting” practically eliminated. The air-cooled refrigeration unit uses CFC-free refrigerant and has a highly efficient heat exchanger. Solenoid valve-bypass operation ensures smooth and continuous running, with minimal vibration.
Easy-to-use, programmable temperature control
A temperature program controller allowing up to 70 set points is fitted as standard. Programing is simple, with a clear digital display of set and actual temperature. Both real time and process time controlled dual set-point temperature programs are available. Set point values or a freely programable ramp function can be selected.
Double security for sample and incubator
The incubators cannot over-heat or over-cool. In the event of a failure, a standby controller with a separate sensor takes over temperature control. Additionally an alarm is sounded. A mechanical safety switch with factory-adjusted release temperature (TWB DIN12880, class 2) protects the incubator against incorrect adjustment of the temperature selector.

400 升內(nèi)部容積冷卻結(jié)晶培養(yǎng)箱。

精確恒溫
溫度由電子控制。根據(jù) DIN-58945,連續(xù)運行的風(fēng)扇可確保整個機柜內(nèi)部和隨時間推移的高精度溫度控制。
加熱和冷卻
連續(xù)可調(diào)的風(fēng)扇安裝電阻加熱器具有低熱“阻力”。它由固態(tài)繼電器控制,避免了步驟和繼電器觸點斷開。這種設(shè)計提供了最大的溫度精度,實際上消除了“慣性”。風(fēng)冷式制冷機組采用無CFC制冷劑,具有高效換熱器。電磁閥旁通操作確保平穩(wěn)連續(xù)運行,振動最小。
易于使用的可編程溫度控制
標配最多可設(shè)置 70 個設(shè)定點的溫度程序控制器。編程簡單,設(shè)置和實際溫度的數(shù)字顯示清晰。提供實時和過程時間控制的雙設(shè)定點溫度程序??梢赃x擇設(shè)定點值或可自由編程的斜坡功能。
樣品和培養(yǎng)箱雙重安全
培養(yǎng)箱不能過熱或過冷。在發(fā)生故障時,帶有獨立傳感器的備用控制器接管溫度控制。此外還會發(fā)出警報。帶有出廠調(diào)節(jié)釋放溫度(TWB DIN12880,2 級)的機械安全開關(guān)可保護培養(yǎng)箱免受溫度選擇器的錯誤調(diào)節(jié)。

MD5-01 Cooled Crystallization Incubator 400 litre 1
MD5-02 Cooled Crystallization Incubator 230 litre 1
MD5-03 Cooled Crystallization Incubator 160 litre 1
MD5-04 Cooled Crystallization Incubator 100 litre 1

Molecular Dimensions品牌介紹

Molecular Dimensions品牌介紹-Molecular Dimensions蛋白結(jié)晶

上海金畔生物代理Molecular Dimensions品牌蛋白結(jié)晶試劑耗材工具等,我們將竭誠為您服務(wù),歡迎訪問Molecular Dimensions官網(wǎng)或者咨詢我們獲取更多相關(guān)Molecular Dimensions品牌產(chǎn)品信息。

Molecular Dimensions 是通過 X 射線晶體學(xué)測定蛋白質(zhì)結(jié)構(gòu)的現(xiàn)代篩網(wǎng)、試劑、其他消耗品和儀器的世界領(lǐng)先供應(yīng)商。 總部位于紐馬克特,在美國設(shè)有辦事處,在亞洲設(shè)有分銷點。 該公司成立于 1998 年,為世界各地的晶體學(xué)家提供專業(yè)產(chǎn)品,通過與旨在開發(fā)和商業(yè)化創(chuàng)新理念的領(lǐng)先科學(xué)家的聯(lián)盟而不斷發(fā)展壯大。 目前的聯(lián)盟包括劍橋分子生物學(xué) MRC 實驗室、倫敦帝國理工學(xué)院、EMBL Hamburg、CEA Saclay、約克結(jié)構(gòu)生物學(xué)實驗室、約克大學(xué)等等。

Molecular Dimensions is a world leading supplier of modern screens, reagents, other consumables and instrumentation for protein structure determination by X-ray crystallography. Headquartered in Newmarket it has offices in the USA and distribution in Asia. Founded in 1998 to provide specialist products for crystallographers across the world, it has grown through alliances with leading scientists aimed at developing and commercializing innovative ideas. Current alliances include the MRC Laboratory of Molecular Biology Cambridge, Imperial College London, EMBL Hamburg, CEA Saclay, York Structural Biology Laboratory, University of York and many more

MD1-106 MIDASplus™ 96 x 10 ml
MD1-107 MIDASplus™ HT-96 96 x 1 ml
MD1-107-FX MIDASplus™ FX-96 pre-filled plate 96 x 100 μl
MD1-126 MIDASplus™ OPTIMAX 1 kit
MD1-76 Power Combo Value Pack (Morpheus? & MIDASplus™) 192 x 10 ml
MD1-76-HT Power Combo Value Pack (Morpheus? & MIDASplus™) HT-96 192 x 1 ml
MDSR-106- MIDASplus™ Single Reagent 100 ml
MDSR-107- MIDASplus™ HT-96 Single Reagent 100 ml
MD1-123 Morpheus Complete 1 kit
MD1-124 Morpheus Complete HT-96 1 kit
MD1-129 Morpheus Fusion 96 x 10 ml
MD1-130 Morpheus Fusion HT-96 96 x 1 ml
MD1-130-FX Morpheus Fusion FX 96 x 100 μl
MD1-46 Morpheus? 96 x 10 ml
MD1-47 Morpheus? HT-96 96 x 1 ml
MD1-47-FX Morpheus? FX-96 pre-filled plate 96 x 100 μl
MD1-47-GREEN Morpheus? HT-96 Green Screen 96 x 1 ml
MD1-76 Power Combo Value Pack (Morpheus? & MIDASplus™) 192 x 10 ml
MD1-76-HT Power Combo Value Pack (Morpheus? & MIDASplus™) HT-96 192 x 1 mL
MD1-93 The Morpheus? Additive Screen 96 x 100 μL
MDSR-46- Morpheus? Single Reagent 100 ml
MDSR-47- Morpheus? HT-96 Single Reagent 100 ml
EBSR-100- Emerald Screen Single Reagent 100 ml
EBSR-250- Emerald Screen Single Reagent 250 ml
MD15-W12-B Wizard Classic 1 & 2 HT-96 96 x 1.7 ml
MD15-W12-T Wizard Classic 1 & 2 (10mL) 96 x 10 ml
MD15-W1-T Wizard Classic 1 (10mL) 48 x 10 ml
MD15-W2-T Wizard Classic 2 (10mL) 48 x 10 ml
MD15-W34-B Wizard Classic 3 & 4 HT-96 96 x 1.7 ml
MD15-W34-T Wizard Classic 3 & 4 (10mL) 96 x 10 ml
MD15-W3-T Wizard Classic 3 (10mL) 48 x 10 ml
MD15-W4-T Wizard Classic 4 (10mL) 48 x 10 ml
MD15-W-BUNDLE Wizard Tube Bundle Special (10ml) 1
MD15-W-BUNDLE-HT96 Wizard Tube Bundle Special (HT96) 1
MD1-13 3D Structure Screen 48 x 10 mL
MD1-13-ECO 3D Structure Eco Screen 48 x 10 mL
MD1-35 Heavy + Light (3D Structure Screen) Twin Pack HT-96 48 x 1 mL (x 2)
MD1-35-ECO Heavy + Light (3D Structure Screen) Twin Pack HT-96 Eco Screen 48 x 1 ml (x 2)
MD1-35-FX Heavy + Light (3D Structure Screen) Twin Pack FX-96 pre-filled plate 48 x 100 μL (x 2)
MDSR-13- 3D Structure Screen Single Reagent 100 ml
MDSR-13-ECO- 3D Structure Screen Eco Single Reagent 100 ml
MDSR-35- Heavy + Light (3D Structure Screen) Twin Pack HT-96 Single Reagent 100 ml
MDSR-35-ECO- Heavy + Light (3D Structure Screen) Twin Pack HT-96 Eco Single Reagent 100 ml

Molecular Dimensions MD1-25 MemSys

Molecular Dimensions MD1-25 MemSys

上海金畔生物代理Molecular Dimensions品牌蛋白結(jié)晶試劑耗材工具等,我們將竭誠為您服務(wù),歡迎訪問Molecular Dimensions官網(wǎng)或者咨詢我們獲取更多相關(guān)Molecular Dimensions品牌產(chǎn)品信息。

MemSys™

A systematic screen spanning the key values of pH, precipitant type / concentration and salts for alpha-type transmembrane proteins using vapour diffusion methods. 48 conditions allowing the pH range, precipitants and salts used in membrane protein crystallization to be screened with detergent containing protein drops. The reagents can be easily arranged in systematic array to facilitate the interpretation of results and the design of further optimization experiments.

Features of MemSys™:

  • A systematic approach to screening for initial crystallization conditions for membrane proteins using vapour diffusion methods.
  • Membrane protein solubility is pushed to the limit to provide more information than previous sparse matrix type screens.
  • Includes the pH, precipitant concentration and type, and salts found to be successful.
  • Primarily designed for alpha-type transmembrane proteins, but has also been successfully applied to beta-type outer membrane proteins.

Developed by members of the So Iwata Lab, Imperial College, London. This product is manufactured under an exclusive licence from Imperial College of Science, Technology & Medicine, London, UK.

使用蒸汽擴散方法對 α 型跨膜蛋白的 pH 值、沉淀劑類型/濃度和鹽的關(guān)鍵值進行系統(tǒng)篩選。 48 種條件允許使用含有蛋白質(zhì)滴劑的洗滌劑篩選膜蛋白質(zhì)結(jié)晶中使用的 pH 值范圍、沉淀劑和鹽。試劑可以很容易地排列在系統(tǒng)陣列中,以方便結(jié)果的解釋和進一步優(yōu)化實驗的設(shè)計。

MemSys™ 的特點:

使用蒸汽擴散方法篩選膜蛋白初始結(jié)晶條件的系統(tǒng)方法。
膜蛋白溶解度被推到極限,以提供比以前稀疏矩陣類型屏幕更多的信息。
包括 pH 值、沉淀劑濃度和類型以及成功的鹽類。
主要設(shè)計用于 α 型跨膜蛋白,但也已成功應(yīng)用于 β 型外膜蛋白。
由倫敦帝國理工學(xué)院 So Iwata 實驗室的成員開發(fā)。本產(chǎn)品在英國倫敦帝國理工學(xué)院的獨家許可下生產(chǎn)。

References? ?參考文獻
“Methods and Results in the crystallization of Membrane proteins” (2003) Ed. Iwata S. (International University Line)

Literature Citing use of Product
1.?Gabdulkhakov AG, Fufina TY, Vasilieva LG, Mueller U, Shuvalov VA. Expression, purification, crystallization and preliminary X-ray structure analysis of wild-type and L(M196)H-mutant Rhodobacter sphaeroides reaction centres. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013; 69(Pt 5): 506-509
2.?Nagarathinam K, Jaenecke F, Nakada-Nakura Y, et al. The multidrug-resistance transporter MdfA from Escherichia coli: crystallization and X-ray diffraction analysis. Acta Crystallogr F Struct Biol Commun. 2017; 73(Pt 7): 423-430
3.?Zabara, A., Chong, J.T.Y., Martiel, I. et al. Design of ultra-swollen lipidic mesophases for the crystallization of membrane proteins with large extracellular domains. Nat Commun. 2018; 9: 544
4.?Lin, Y. Crystallization and preliminary X-ray diffraction studies of melibiose permease. bioRxiv. 2020; 173740
Product # Product Name Unit Size
MD1-04 The Membrane Protein Combination 96 x 10 ml
MD11-60-33 Hanging Drop Starter Kit MemStart™ + MemSys™ HT-96 1 kit
MD1-25 MemSys™ 48 x 10 ml
MD1-33 MemStart™ + MemSys™ HT-96 96 x 1 ml
MDSR-25 MemSys™ Single Reagent 100 ml
MDSR-33 MemStart™ + MemSys™ HT-96 Single Reagent 100 ml

Molecular Dimensions蛋白結(jié)晶

Molecular Dimensions蛋白結(jié)晶

上海金畔生物代理Molecular Dimensions品牌蛋白結(jié)晶試劑耗材,歡迎新老客戶訪問Molecular Dimensions官網(wǎng)或者咨詢我們獲取更多產(chǎn)品信息。

Molecular Dimensions是世界的現(xiàn)代篩選,試劑,其他消耗品和儀器的供應(yīng)商,通過X射線晶體學(xué)確定蛋白質(zhì)結(jié)構(gòu)。該公司成立于1998年,為世界各地的晶體學(xué)家提供專業(yè)產(chǎn)品,并與的科學(xué)家結(jié)成聯(lián)盟,旨在開發(fā)和商業(yè)化創(chuàng)新理念。該公司目前有20多個項目處于不同的發(fā)展階段,從用于晶體生長的新型屏幕和試劑,新的實驗室塑料制品到各種儀器。該公司去年推出了許多獨特的產(chǎn)品;RUBIC和Durham蛋白質(zhì)穩(wěn)定性篩選,BCS篩選,MIDASplus,Crystallophore No1,Cryo-EM ngrdi-box存儲圓盤,無瓶冷凍環(huán)系統(tǒng),ClearVue QuickTear條帶和DiffraX。

  • 品牌國別:?英國
  • 品牌簡介:?Molecular Dimensions 英國Molecular Dimensions?
  • 官網(wǎng):www.moleculardimensions.com
  • 英國Molecular Dimensions歐洲權(quán)威蛋白質(zhì)結(jié)晶試劑與耗材生產(chǎn)商 產(chǎn)品分類: 1.Crystal Growth Screens 晶體生長試劑 ⑴Soluble protein screen 可溶性蛋白結(jié)晶試劑 ⑵Membrane Protein Crystallization 膜蛋白結(jié)晶化試劑 ①Membrane Protein Crystal Growth Screens > 膜蛋白晶體生長試劑-基于成功。

Molecular Dimensions

英國Molecular Dimensions? www.moleculardimensions.com
英國Molecular Dimensions歐洲權(quán)威蛋白質(zhì)結(jié)晶試劑與耗材生產(chǎn)商
產(chǎn)品分類:

1.Crystal Growth Screens 晶體生長試劑

⑴Soluble protein screen 可溶性蛋白結(jié)晶試劑
⑵Membrane Protein Crystallization 膜蛋白結(jié)晶化試劑
①Membrane Protein Crystal Growth Screens > 膜蛋白晶體生長試劑-基于成功的膜蛋白結(jié)晶的現(xiàn)代化的試劑。
②detergent 去垢劑-去垢劑和膜蛋白結(jié)晶化的試劑
⑶Protein Complex Screens >蛋白復(fù)合結(jié)晶化-這些試劑滿足維持蛋白-蛋白間交互作用和減少復(fù)合物可溶性的雙重需要。
⑷Nuclear Receptor Ligand Binding Domains >向心配合體綁定區(qū)域的結(jié)晶化-提供向心配合體綁定區(qū)域的結(jié)晶化試劑。

2.Optimization > 優(yōu)化試劑

⑴Single screen reagents >單個的蛋白結(jié)晶試劑-可以提供晶體生長試劑盒中的單獨的結(jié)晶試劑。
⑵Buffer concentrates >緩沖溶液
⑶Stock Reagents >
PEG Precipitants >
Jeffamines >
Other Precipitants >
⑷The Really Useful Buffer Kit >非常有用的緩沖試劑盒
⑸Optimization screens >晶體優(yōu)化試劑-提供用于改善晶體質(zhì)量的凝膠狀表面,小分子以及去垢劑。
⑹Crystal growth oils >晶體生長用油類-提供批量化結(jié)晶用油類。

3. High-Throughput Consumables >高通量的晶體生長耗材

⑴High-Throughput Crystal Growth Screens >
⑵High-Throughput Plates >
①sitting drop plates
②hanging drop
③microbatch
⑶High-Throughput Adhesive Seals >

4.Plates and Accessories >

5. Cryocrystallography >

6. Protein Expression Media and Protein Production >

⑴SelenoMet Medium >
⑵Protein Expression Media >
⑶Protein Refolding >
⑷GeBaFlex Dialysis and Electroelution tubes >

7.books 工具書

包括以下蛋白結(jié)晶系列工具書:
Preparation & Analysis of Protein Crystals
Practical Protein Crystallography
Principles of Protein X-Ray Crystallography
Methods in Enzymology 276
Methods in Enzymology 277
Protein Methods
Protein Crystallization Techniques Strategies & Tips
Crystallization of Nucleic Acids and Proteins
Crystallization of Nucleic Acids and Proteins
Fundamentals of Crystallography
Crystals and Life. A Personal Journey
Understanding Diseases by Understanding Proteins
ICCBM 9 Proceedings
Methods and Results in the Crystallization of Membrane Proteins
Outline of Crystallography for Biologists

8.Tools >一系列對您實驗有幫助的工具。

Microtools >微型工具-包括Box of Micro Tools;Micro Knife;Micro Scraper;Micro Needle;Micro Spade;Micro Spatula;Micro Chisel;Micro Prober;Micro Scale;Microtool Handle

9. Mosquito >Mosquito-液滴處理的新工具,其優(yōu)點是:緊湊,精確,便利,靈活,易于操作,無交叉污染,可隨意使用。

10. CrystalPro – Crystal Imaging Systems >

11. Crystal DUVI- DLS/ UV/White Light Imagers >

12. Single Station Personal Pipettor >

13. Incubators >晶體生長孵化器

Cooled Crystallization Incubator 390 litre
Cooled Crystallization Incubator 250 litre
Cooled Crystallization Incubator 180 litre
Cooled Crystallization Incubator 100 litre

14. Crystallography Giftware >

Molecular Dimensions Ltd. was founded in 1998 to provide crystallographers in the UK and Europe with products tailored to meet their specific demands from a local source. During these early days Molecular Dimensions formed some very strong alliances with leading crystallographers to develop and commercialise numerous unique ideas. Today these alliances are just as strong with our new crystalisation screen, MorpheusTM, being the latest example (MRC Laboratory of Molecular Biology, Cambridge, UK).

In addition to the continued development of our range of unique and intelligent screen solutions, the company has also been required to expand both in its geographical location (Offices in USA and Distribution in Asia) but also in our product portfolio with many new and inventive products being included, most recently CrystalDUVITM. Molecular Dimensions Ltd. continues to be an exciting company to be involved with not only a full pipeline of development ideas but also the willingness and ability to move very quickly and respond to the requirements of the crystallographic community.

We have also added several items of hardware to our catalogue, all of which are of the very highest quality and at the cutting edge of their respective technologies, e.g MosquitoTM, CrystalProTM and RuMed? Incubators. These products continue to evolve through the close collaborative realtionships between Molecular Dimensions and TTP Labtech , TriTek Corp and Rubarth Apparat GmbH.

At Molecular Dimensions Ltd. we focus our efforts on providing you, the crystallographer, with Intelligent Solutions rather than selling everything and anything, thus making it easier for you to find exactly what you need when you need it. We hope that you find everything that you require, but we are always happy to hear any comments, recommendations or ideas that you may have.

Molecular Dimensions部分產(chǎn)品的詳細列表:

產(chǎn)品 貨號 品牌
Sealing Grease MD6-02 molecular Dimensions
Sitting Drop Bridges MD3-17 molecular Dimensions
Diacon™ MD6-71 molecular Dimensions
Media Optimization Kit™ (Powder) MD12-100 molecular Dimensions
XRL Plate trial pack with CrystalClene Slips MD3-11T molecular Dimensions
SG1™ Screen MD1-88 molecular Dimensions
Super2 Combo Value Pack (JCSG-plus™?& PACT premier™) MD1-75 molecular Dimensions
27.5L Bench Top Incubator (Fully-programmable) MD5-601 molecular Dimensions
10× – 65× zoom with incident and transmitted light MD5-913 molecular Dimensions
Fine Tweezers MD9-25 molecular Dimensions
ClearVue Sheets (UV friendly) MD6-01S molecular Dimensions
QuickTear ClearVue Sheets (perforated strips) HW MD6-41 molecular Dimensions
Hand Roller MD11-04 molecular Dimensions
Detachable Polarizer Set (use with MD5-912 and MD5-913) MD5-921 molecular Dimensions
Empty FLIQ FPLC Columns, 1ml/5ml/10ml/20ml FLIQ Columns molecular Dimensions
Elite protein ladders PAL-EPL-500/2500 molecular Dimensions
NR-LBD™ MD1-24 molecular Dimensions
NR-LBD™ Extension MD1-26 molecular Dimensions
The Nuclear Receptor Combination MD1-27 molecular Dimensions
NR-LBD™ + NR-LBD™ Extension HT-96 MD1-34 molecular Dimensions
MemSys™ MD1-25 molecular Dimensions
MemGold™ MD1-39 molecular Dimensions
MemGold 2 MD1-63 molecular Dimensions
MemGoldMeso™ MD1-114 molecular Dimensions
MemStart™ MD1-21 molecular Dimensions
Morpheus? MD1-46 molecular Dimensions
Morpheus? II MD1-91 molecular Dimensions
ProPlex™ MD1-38 molecular Dimensions